Stochastic Chemical Reaction Systems in Biology

This book provides an introduction to the analysis of stochastic dynamic models in biology and medicine. The main aim is to offer a coherent set of probabilistic techniques and mathematical tools which can be used for the simulation and analysis of various biological phenomena. These tools are illus...

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Bibliographic Details
Main Authors: Qian, Hong, Ge, Hao (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2021, 2021
Edition:1st ed. 2021
Series:Lecture Notes on Mathematical Modelling in the Life Sciences
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • 1. Introduction
  • Part I Essentials of Deterministic and Stochastic Chemical Kinetics: 2. Kinetic Rate Equations and the Law of Mass Action
  • 3. Probability Distribution and Stochastic Processes
  • 4. Large Deviations and Kramers’ rate formula
  • 5. The Probabilistic Basis of Chemical Kinetics
  • 6. Mesoscopic Thermodynamics of Markov Processes
  • 7. Emergent Macroscopic Chemical Thermodynamics
  • 8. Phase Transition and Mesoscopic Nonlinear Bistability
  • Part III Stochastic Kinetics of Biochemical Systems and Processes: 9. Classic Enzyme Kinetics—The Michaelis-Menten and Briggs-Haldane Theories
  • 10. Single-Molecule Enzymology and Driven Biochemical Kinetics with Chemostat
  • 11. Stochastic Linear Reaction Kinetic Systems
  • 12. Nonlinear Stochastic Reaction Systems with Simple Examples
  • 13. Kinetics of the Central Dogma of Molecular Cell Biology
  • 14. Stochastic Macromolecular Mechanics and Mechanochemistry
  • Part IV Epilogue: Beyond Chemical Reaction Kinetics: 15. Landscape, Attractor-State Switching, and Differentiation
  • 16. Nonlinear Stochastic Dynamics: New Paradigm and Syntheses
  • References
  • Index