Triclosan in single use medical devices for preventing infections a review of clinical effectiveness, safety and guidelines

Triclosan is a synthetic antimicrobial compound. At low concentrations, triclosan suppresses the growth of numerous bacteria, and at higher concentrations, it can rapidly kill bacteria. Due to its antiseptic and disinfectant properties, triclosan is used in numerous products, including personal care...

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Bibliographic Details
Main Authors: Brett, Kendra, Argáez, Charlene (Author)
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health July 11, 2019, 2019
Edition:Version 1.0
Series:CADTH rapid response report: summary with critical appraisal
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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653 |a Anti-Infective Agents, Local / therapeutic use 
653 |a Canada 
653 |a Surgical Wound Infection / prevention & control 
653 |a Treatment Outcome 
653 |a Evidence-Based Practice 
653 |a Triclosan / therapeutic use 
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520 |a Triclosan is a synthetic antimicrobial compound. At low concentrations, triclosan suppresses the growth of numerous bacteria, and at higher concentrations, it can rapidly kill bacteria. Due to its antiseptic and disinfectant properties, triclosan is used in numerous products, including personal care products (e.g., hand soap), household items (e.g., cutting boards), and medical devices (e.g. sutures, catheters). Wider use of antiseptics and antimicrobials has been suggested for surgical practice, however, it is unclear whether using triclosan on single use medical devices or consumables (e.g., sutures) is likely to provide a significant benefit in reducing infections in hospitalized patients. The purpose of this report is to synthesize and critically appraise the available evidence on the clinical effectiveness and safety of using triclosan on single use medical devices or consumables for infection prevention in hospitalized patients. Additionally, evidence-based guidelines regarding the use of triclosan on medical devices or consumables for infection prevention will be reviewed. This information may be used to inform decision making relating to health policy of the use of triclosan on single use medical devices or consumables