Interventions to improve pharmacological adherence among adults with psychotic spectrum disorders, bipolar disorder, and posttraumatic stress disorder

The goal of this report is to synthesize evidence examining the effectiveness of interventions to improve medication adherence in patients with psychotic spectrum disorders, bipolar disorder, and PTSD; the effect of these interventions on patient outcomes; and the related costs and any associated in...

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Bibliographic Details
Main Author: Kondo, Karli
Corporate Authors: Portland VA Medical Center Evidence-based Synthesis Program Center, Quality Enhancement Research Initiative (U.S.), United States Department of Veterans Affairs
Format: eBook
Language:English
Published: Washington (DC) Department of Veterans Affairs, Health Services Research & Development Service November 2015, 2015
Series:Evidence-based synthesis program
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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245 0 0 |a Interventions to improve pharmacological adherence among adults with psychotic spectrum disorders, bipolar disorder, and posttraumatic stress disorder  |h Elektronische Ressource  |c principal investigator, Karli Kondo ; co-investigators, Allison Low [and 8 others] ; prepared by Evidence-based Synthesis Program (ESP) Center, Portland VA Medical Center 
260 |a Washington (DC)  |b Department of Veterans Affairs, Health Services Research & Development Service  |c November 2015, 2015 
300 |a 1 PDF file (iv, 131 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
710 2 |a Portland VA Medical Center  |b Evidence-based Synthesis Program Center 
710 2 |a Quality Enhancement Research Initiative (U.S.) 
710 2 |a United States  |b Department of Veterans Affairs 
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520 |a The goal of this report is to synthesize evidence examining the effectiveness of interventions to improve medication adherence in patients with psychotic spectrum disorders, bipolar disorder, and PTSD; the effect of these interventions on patient outcomes; and the related costs and any associated intervention specific harms 
520 |a Interventions at the organization level may involve system-level interventions, such as financial incentives or reducing economic barriers through cost sharing; blister packaging for improving patient recall and tracking; and care coordination. Other interventions implemented at the organizational level include information and communication technology, such as electronic monitoring (e-monitoring), refill reminders via telephone or short message service (SMS); or other strategies, A recent review of interventions for medication adherence in patients with chronic illness found that educational interventions and case management were consistent in improving adherence across different clinical conditions, as were clinical reminders, pharmacist-led multicomponent approaches, and reducing out of pocket expenses for patients. This review examined interventions for medication adherence in patients with depression, but did not include other serious mental illnesses.  
520 |a Non-adherence to medication is a serious problem in the United States (US). It is associated with increased emergency department visits and hospitalizations, higher costs of care, and greater mortality. For patients with serious mental illness, including schizophrenia and other psychotic spectrum disorders, bipolar disorder, and posttraumatic stress disorder (PTSD), adherence to psychopharmacological and/or non-psychopharmacological medications is an important concern. There are a wide range of interventions for medication adherence. Interventions that target patients include psychosocial and behavioral interventions, including cognitive behavioral therapy (CBT) and Motivational Interviewing (MI), shared decision-making, customized adherence enhancement (CAE), Adherence and Compliance Therapies, and interventions involving family members. Other interventions target providers, such as provider education and training in MI.