Comparative effectiveness of drug therapy for rheumatoid arthritis, and psoriatic arthritis in adults

This report from the RTI-University of North Carolina Evidence-based Practice Center summarizes the evidence on the comparative efficacy, effectiveness, and harms of corticosteroids, synthetic DMARDs, and biologic DMARDs in the treatment of patients with either rheumatoid arthritis (RA) or psoriatic...

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Bibliographic Details
Main Author: Donahue, Katrina E.
Corporate Authors: United States Agency for Healthcare Research and Quality, RTI International-University of North Carolina Evidence-based Practice Center
Format: eBook
Language:English
Published: [Rockville, MD Agency for Healthcare Research and Quality 2007, 2007]
Series:Comparative effectiveness review
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Donahue, Katrina E. 
245 0 0 |a Comparative effectiveness of drug therapy for rheumatoid arthritis, and psoriatic arthritis in adults  |h Elektronische Ressource  |c prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by RTI-University of North Carolina Evidence-based Practice Center ; investigators, Katrina E. Donahue ... [et al.] 
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505 0 |a Includes bibliographical references 
653 |a Comparative Effectiveness Research 
653 |a Antirheumatic Agents / therapeutic use 
653 |a Arthritis, Rheumatoid / drug therapy 
653 |a Arthritis, Psoriatic / drug therapy 
710 2 |a United States  |b Agency for Healthcare Research and Quality 
710 2 |a RTI International-University of North Carolina Evidence-based Practice Center 
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490 0 |a Comparative effectiveness review 
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520 |a This report from the RTI-University of North Carolina Evidence-based Practice Center summarizes the evidence on the comparative efficacy, effectiveness, and harms of corticosteroids, synthetic DMARDs, and biologic DMARDs in the treatment of patients with either rheumatoid arthritis (RA) or psoriatic arthritis (PsA). The key questions (KQs) were developed through a public process in conjunction with the Scientific Resource Center at the Oregon Health and Science University. The KQs are as follows: KQ 1. For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in their ability to reduce patient-reported symptoms, to slow or limit progression of radiographic joint damage, or to maintain remission? KQ 2. For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in their ability to improve functional capacity or quality of life? KQ 3. For patients with rheumatoid arthritis or psoriatic arthritis, do drug therapies differ in harms, tolerability, adherence, or adverse effects? KQ 4. What are the comparative benefits and harms of drug therapies for rheumatoid arthritis and psoriatic arthritis in subgroups of patients based on stage of disease, history of prior therapy, demographics, concomitant therapies, or comorbidities?