Icatibant for patients with type III hereditary angioedema a review of clinical effectiveness and harms

Icatibant, a selective bradykinin B2 receptor antagonist, has been approved in many countries worldwide for the symptomatic treatment of acute attacks of types I and II hereditary angioedema (HAE) in adults since 2008. It was reported that icatibant was successful in the prevention of angioedema aft...

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Bibliographic Details
Corporate Authors: Canadian Agency for Drugs and Technologies in Health Rapid Response Service, Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: [Ottawa] Canadian Agency for Drugs and Technologies in Health February 6, 2014, 2014
Series:Rapid response report : summary with critical appraisal
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Icatibant, a selective bradykinin B2 receptor antagonist, has been approved in many countries worldwide for the symptomatic treatment of acute attacks of types I and II hereditary angioedema (HAE) in adults since 2008. It was reported that icatibant was successful in the prevention of angioedema after thyroid biopsy in HAE type I. Icatibant has also reportedly been used for type III HAE, although it is not licensed for this indication. The objective of this report is to review the therapeutic and prophylactic effectiveness and harms of icatibant in the treatment of type III HAE.
Item Description:Title from PDF caption
Physical Description:1 PDF file (10 pages) illustration