Roadmap for narratively describing effects of interventions in systematic reviews

Accurately describing treatment effects using plain language and narrative statements is a critical step in communicating research findings to end users. However, the process of developing these narratives has not been historically guided by a specific framework. The Agency for Healthcare Research a...

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Bibliographic Details
Main Author: Gerrity, Martha
Corporate Authors: Scientific Resource Center (Portland, Or.), United States Agency for Healthcare Research and Quality
Format: eBook
Language:English
Published: Rockville, MD Agency for Healthcare Research and Quality 2020, November 2020
Series:Methods white paper
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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520 |a Accurately describing treatment effects using plain language and narrative statements is a critical step in communicating research findings to end users. However, the process of developing these narratives has not been historically guided by a specific framework. The Agency for Healthcare Research and Quality Evidence-based Practice Center Program developed guidance for narrative summaries of treatment effects that identifies five constructs. We explicitly identify these constructs to facilitate developing narrative statements (1) size of effect, (2) direction of effect, (3) clinical importance, (4) statistical significance, and (5) strength or certainty of evidence. These constructs clearly overlap. It may not always be feasible to address all five constructs. Based on context and intended audience, investigators can assess which constructs will be most important to address in narrative statements