Acoustic radiation force impulse imaging for diagnosis and monitoring of liver fibrosis in patients with hepatitis C a review of diagnostic accuracy, clinical effectiveness, cost-effectiveness, and guidelines

Acoustic Radiation Force Imaging (ARFI) is an emerging non-invasive procedure that is a potential alternative to liver biopsy. One significant advantage of ARFI imaging is that it is integrated into a conventional ultrasonographic system. This also allows for a sonographic evaluation of the liver to...

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Bibliographic Details
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health 2016, 18 April 2016
Series:Rapid response report: summary with critical appraisal
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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245 0 0 |a Acoustic radiation force impulse imaging for diagnosis and monitoring of liver fibrosis in patients with hepatitis C  |h Elektronische Ressource  |b a review of diagnostic accuracy, clinical effectiveness, cost-effectiveness, and guidelines  |c prepared by Canadian Agency for Drugs and Technologies in Health 
246 3 1 |a ARFI for the diagnosis and monitoring of liver fibrosis in patients with hepatitis C 
260 |a Ottawa (ON)  |b Canadian Agency for Drugs and Technologies in Health  |c 2016, 18 April 2016 
300 |a 1 PDF file (32 pages) 
505 0 |a Includes bibliographical references 
710 2 |a Canadian Agency for Drugs and Technologies in Health 
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989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a Rapid response report: summary with critical appraisal 
500 |a Title from PDF caption. - "CADTH Rapid Response Service." 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK362186  |3 Volltext 
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520 |a Acoustic Radiation Force Imaging (ARFI) is an emerging non-invasive procedure that is a potential alternative to liver biopsy. One significant advantage of ARFI imaging is that it is integrated into a conventional ultrasonographic system. This also allows for a sonographic evaluation of the liver to be performed simultaneously with ARFI; this provides patients an ideal 'one-stop shop' for noninvasive liver evaluation, even in patients with a significant amount of ascites. ARFI is a technology designed to measure shear wavefront at multiple locations to calculate tissue stiffness. The wave velocity determines tissue stiffness through a simple method: the stiffer the tissue, the greater velocity. The purpose of this Rapid Response report is to review the clinical effectiveness, diagnostic accuracy, cost-effectiveness, and evidence-based guidelines regarding the use of ARFI for detecting and grading liver fibrosis in patients with hepatitis C. This report represents an update to a previous 2012 report that reviewed the clinical and cost-effectiveness evidence of diagnosis and monitoring of liver fibrosis among patients with hepatitis C; that report found moderate to high accuracy for FibroTest, transient elastography (known as FibroScan), and aminotransferase-to-platelet ratio index (APRI) with generally higher accuracy for cirrhosis compared with earlier fibrosis stages