Alpha2-adrenergic agonists for the reduction or discontinuation of opioids or opioid substitution therapy a review of clinical effectiveness and guidelines

Using alpha2-adrenergic agonists may be effective in opioid reduction or discontinuation relative to other supportive interventions or opioid substitution therapies. Further, there may be differences in effectiveness between alpha2-adrenergic agonists in themselves. This review considered the eviden...

Full description

Bibliographic Details
Main Authors: Jahagirdar, Deepa, Campbell, Kaitryn (Author)
Corporate Authors: Canadian Agency for Drugs and Technologies in Health, Canadian Agency for Drugs and Technologies in Health Rapid Response Service
Format: eBook
Language:English
Published: Ottawa CADTH 2018, February 23, 2018
Series:CADTH rapid response report: summary with critical appraisal
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
LEADER 01561nam a2200253 u 4500
001 EB002000554
003 EBX01000000000000001163455
005 00000000000000.0
007 tu|||||||||||||||||||||
008 210907 r ||| eng
100 1 |a Jahagirdar, Deepa 
245 0 0 |a Alpha2-adrenergic agonists for the reduction or discontinuation of opioids or opioid substitution therapy  |h Elektronische Ressource  |b a review of clinical effectiveness and guidelines  |c Deepa Jahagirdar and Kaitryn Campbell 
260 |a Ottawa  |b CADTH  |c 2018, February 23, 2018 
300 |a 1 PDF file (26 pages)  |b illustration 
505 0 |a Includes bibliographic references 
700 1 |a Campbell, Kaitryn  |e [author] 
710 2 |a Canadian Agency for Drugs and Technologies in Health 
710 2 |a Canadian Agency for Drugs and Technologies in Health  |b Rapid Response Service 
041 0 7 |a eng  |2 ISO 639-2 
989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a CADTH rapid response report: summary with critical appraisal 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK531931  |3 Volltext 
082 0 |a 610 
520 |a Using alpha2-adrenergic agonists may be effective in opioid reduction or discontinuation relative to other supportive interventions or opioid substitution therapies. Further, there may be differences in effectiveness between alpha2-adrenergic agonists in themselves. This review considered the evidence and guidelines to this effect, to explore whether alpha2-adrenergic agonists could assist in reducing the burden of opioid dependence