NTP developmental and reproductive toxicity technical report on the prenatal development studies of vinpocetine (CASRN 42971-09-5) in Sprague Dawley (Hsd: Sprague Dawley SD) rats and New Zealand white (Hra: Nzw spf) rabbits (Gavage studies)

Significant decreases in mean maternal body weight gains were observed in the 150 and 300\smg/kg groups and a treatment-related decrease in feed consumption in these groups. An exposure-related effect was observed on embryo-fetal survival in the 300\smg/kg group with an increase in early resorptions...

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Bibliographic Details

Corporate Author:	National Toxicology Program (U.S.)
Format:	eBook
Language:	English
Published:	Research Triangle Park, North Carolina, USA National Toxicology Program, Public Health Service, U.S. Department of Health and Human Services 2020, June 2020
Series:	NTP developmental and reproductive toxicity technical report
Subjects:	United States Models, Animal Fetal Development Toxicity Tests Rats, Sprague-dawley Phosphodiesterase Inhibitors / Toxicity Nootropic Agents Rabbits
Online Access:	http://www.ncbi.nlm.nih.gov/books/NBK559694
Collection:	National Center for Biotechnology Information - Collection details see MPG.ReNa