Isobutyl nitrite, β-Picoline, and some acrylates
This volume of the IARC Monographs provides evaluations of the carcinogenicity of isobutyl nitrite, β-picoline, methyl acrylate, ethyl acrylate, 2-ethylhexyl acrylate, and trimethylolpropane triacrylate. The four acrylates evaluated are chemicals with a high production volume that are produced world...
| Corporate Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Lyon, France
International Agency for Research on Cancer, World Health Organization
December 2019, 2019
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| Series: | IARC monographs on the evaluation of carcinogenic risks to humans
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| Subjects: | |
| Online Access: | |
| Collection: | National Center for Biotechnology Information - Collection details see MPG.ReNa |
| Summary: | This volume of the IARC Monographs provides evaluations of the carcinogenicity of isobutyl nitrite, β-picoline, methyl acrylate, ethyl acrylate, 2-ethylhexyl acrylate, and trimethylolpropane triacrylate. The four acrylates evaluated are chemicals with a high production volume that are produced worldwide. Methyl acrylate is used in the production of acrylic fibres and fire-retardant fabrics. Ethyl acrylate is one of the principal monomers used worldwide in the production of styrene-based polymers, which can be used for medical and dental items. Ethyl acrylate is also used in surface coatings for textiles, paper, leather, and food contact materials, and as a food flavouring agent. 2-Ethylhexyl acrylate is used as a plasticizing co-monomer in the production of resins for pressure-sensitive adhesives, latex paints, reactive diluent/cross-linking agents, textile and leather finishes, and coatings for paper. Trimethylolpropane triacrylate, available as a technical-grade product that also contains incomplete reaction products, is used primarily in production of ultraviolet-curable inks, paint additives, coatings, and adhesives. β-Picoline, a methyl pyridine, is widely used as a starting material for pesticides (e.g. chlorpyrifos) and pharmaceuticals (e.g. vitamin B3). It is also used as a flavouring substance in foods and beverages. Isobutyl nitrite is used an intermediate in the syntheses of solvents and fuels, and exposures also occur through its use as a recreational drug. Exposure to all six agents considered may occur in the general population as well as in various occupational settings. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of environmental or occupational exposure to these agents |
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| Item Description: | "This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 5-12 June 2018." |
| Physical Description: | 1 PDF file (vii, 175 pages) illustrations |
| ISBN: | 9789283201892 9789283201601 |