CADTH Canadian Drug Expert Committee recommendation: Insulin degludec and liraglutide (Xultophy -- Novo Nordisk Canada Inc.) indication : adjunct to lifestyle modifications, for the once-daily treatment of adults with type 2 diabetes mellitus (T2DM) to improve glycemic control in combination with metformin, with or without sulfonylurea, when these combined with basal insulin (less than 50 units daily) or liraglutide (less than or equal to 1.8 mg daily), do not provide adequate glycemic control

The CADTH Canadian Drug Expert Committee (CDEC) recommends that insulin degludec and liraglutide (IDegLira) should be reimbursed as an adjunct to lifestyle modification, for the once-daily treatment of adults with T2DM to improve glycemic control in combination with metformin (MET), with or without...

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Bibliographic Details
Corporate Authors: CADTH Canadian Drug Expert Committee, Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) CADTH October 2019, 2019
Edition:Version: 1.0
Series:CADTH common drug review
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:The CADTH Canadian Drug Expert Committee (CDEC) recommends that insulin degludec and liraglutide (IDegLira) should be reimbursed as an adjunct to lifestyle modification, for the once-daily treatment of adults with T2DM to improve glycemic control in combination with metformin (MET), with or without sulfonylurea (SU), when these, combined with basal insulin (at doses of 20 to 50 units per day) do not provide adequate glycemic control, only if the following conditions are met : Conditions for Reimbursement. Discontinuation criteria: 1. IDegLira should be discontinued if the patient does not achieve a desirable level of glycemic control despite receiving a maximum dose of IDegLira (50 units of insulin degludec [IDeg] and 1.8 mg of liraglutide) after 26 weeks of treatment. Pricing condition: 1. Drug plan costs for IDegLira should not exceed the cost of the least costly glucagon-like peptide-1 receptor agonist (GLP-1 RA) plus the least costly basal insulin administered separately or in combination
Item Description:"Final."
Physical Description:1 PDF file (10 pages)