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210901 ||| eng |
| 020 |
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|a 9783030661472
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| 100 |
1 |
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|a Sánchez Morgado, José M.
|e [editor]
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| 245 |
0 |
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|a Experimental Design and Reproducibility in Preclinical Animal Studies
|h Elektronische Ressource
|c edited by José M. Sánchez Morgado, Aurora Brønstad
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| 250 |
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|a 1st ed. 2021
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| 260 |
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|a Cham
|b Springer International Publishing
|c 2021, 2021
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| 300 |
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|a VI, 277 p. 52 illus., 39 illus. in color
|b online resource
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| 505 |
0 |
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|a An introduction to reproducibility in the context of animal research -- Rodent Genetics -- Animal and environmental factors that influence reproducibility -- Microbiology and Microbiome -- Effects of untreated pain, anesthesia and analgesia in animal experimentation -- Why do we need a statistical experiment design -- Statistical tests and Sample size calculations -- Design of experiments -- Scholarly Publishing and Scientific Reproducibility -- Systematic reviews -- Planning animal experiments
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| 653 |
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|a Medicine / Research
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| 653 |
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|a Biostatistics
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| 653 |
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|a Biology / Research
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| 653 |
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|a Veterinary Science
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| 653 |
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|a Biomedical Research
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| 653 |
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|a Veterinary medicine
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| 653 |
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|a Biometry
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| 700 |
1 |
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|a Brønstad, Aurora
|e [editor]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
0 |
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|a Laboratory Animal Science and Medicine
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| 028 |
5 |
0 |
|a 10.1007/978-3-030-66147-2
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-030-66147-2?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 636.089
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| 520 |
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|a This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. The book addresses advanced undergraduates, graduate students and all scientists working with animals
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