Hi-C Data Analysis Methods and Protocols
This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Writ...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Humana
2022, 2022
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| Edition: | 1st ed. 2022 |
| Series: | Methods in Molecular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Normalization of Chromosome Contact Maps: Matrix Balancing and Visualization
- Methods to Assess the Reproducibility and Similarity of Hi-C Data
- Methods for the Analysis of Topological Associating Domains (TADs)
- Methods for the Differential Analysis of Hi-C D
- Visualising and Annotating Hi-C Data
- Hi-C Data Formats
- Analysis of Hi-C Data for Discovery of Structural Variations In Cancer
- Metagenomes Binning using Proximity-Ligation Data
- Generating High-resolution Hi-C Contact Maps Of Bacteria
- Computational Tools for the Multiscale Analysis of HiC Data in Bacterial Chromosomes
- Analysis of HiChIP Data
- The Physical Behavior of Interphase Chromosomes: Polymer Theory and Coarse-Grain Computer Simulations
- Polymer Folding Simulations from Hi-C Data
- Predictive Polymer Models for 3D Chromosome Organization
- Polymer Modeling of 3D Epigenome Folding: Application to Drosophila
- A Polymer Physics Model To Dissect Genome Organization In Healthy And Pathological Phenotypes
- The 3D Organization of Chromatin Colors in Mammalian Nuclei
- Modeling the 3D Genome using Hi-C and Nuclear Lamin-Genome Contacts