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|a books978-3-03936-947-8
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|a 9783039369461
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|a 9783039369478
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|a Leitão, Jorge H.
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|a Microbial Virulence Factors
|h Elektronische Ressource
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|a Basel, Switzerland
|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2020
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|a 1 electronic resource (400 p.)
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|a virulence factors
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|a truA
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|a cystic fibrosis
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|a gelatin
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|a interspecies interactions
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|a sputum
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|a persistence
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|a actin
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|a grimelysin
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|a autotransporter
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|a mucin
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|a UTIs
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|a Candida albicans
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|a Hfq
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|a Salmonella enterica serovar Typhimurium
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|a Candida
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|a T3SS
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|a serine proteases
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|a omics analysis
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|a host-pathogen interaction
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|a Enterobacter
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|a SPATEs
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|a differential expression proteins
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|a fungicidal activity
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|a motility
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|a SsNsd1
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|a topology mapping
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|a apple proliferation
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|a primary ciliary dyskinesia
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|a 5637 bladder cells
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|a Actinomycetales
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|a EDTA
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|a antimicrobial peptides
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|a effector protein
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|a LysR-family
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|a SpyCatcher
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|a Biology, life sciences / bicssc
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|a pathogenomics
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|a Trueperella pyogenes
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|a Dickeya solani
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|a biofilm formation
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|a proteomics analysis
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|a antibiotic resistance
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|a bacterial pathogens
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|a compound appressorium
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|a actin proteolysis
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|a virulence factor
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|a covalent labeling
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|a chronic infection
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|a cytotoxicity
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|a protealysin
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|a Aeromonas hydrophila
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|a pathogenicity
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|a Research and information: general / bicssc
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|a fungal pathogens
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|a virulence
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|a immune evasion
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|a Pseudomonas aeruginosa
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|a bacterial invasion
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|a bacteria
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|a inflammation
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|a immune response
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|a bacterial surface protein
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|a apple
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|a protease ECP 32
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|a usg
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|a small noncoding regulatory RNAs
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|a Burkholderia cepacia complex
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|a metalloproteinases
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|a intracellular survival
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|a inter-kingdom protection
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|a lon expression
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|a pyolysin
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|a blood-brain barrier
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|a antimicrobial peptide
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|a infection
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|a protease Lon
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|a Klebsiella
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|a fluconazole
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|a whole genome sequencing
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|a complement
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|a ΔlahS
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|a global regulator
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|a Bordetella pertussis
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|a solute-binding proteins
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|a meningitis
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|a phytoplasma
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|a pectinolytic enzymes
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|a biofilm
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|a coagulase-negative staphylococci
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|a Enterobacterales
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|a resistance to stress
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|a Sclerotinia sclerotiorum
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|a anti-virulence
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|a morphology
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|a type III secretion system
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|a serum resistance
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|a hyphae
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|a outer membrane vesicles (OMVs)
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|a two-dimensional electrophoresis
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|a oxidative stress
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|a microbial virulence factors
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|a Citrobacter
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|a blood-cerebrospinal fluid barrier
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|a gene expression
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|a plant pathogen
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|a replicative niche
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|a manipulation
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|a Leitão, Jorge H.
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041 |
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7 |
|a eng
|2 ISO 639-2
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|b DOAB
|a Directory of Open Access Books
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|a Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
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5 |
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|a 10.3390/books978-3-03936-947-8
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856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/69041
|z DOAB: description of the publication
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|u https://www.mdpi.com/books/pdfview/book/2810
|7 0
|x Verlag
|3 Volltext
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|a 414
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|a 000
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|a 580
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|a 380
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|a Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic.
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