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Characterization and Clinical Management of Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis...

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Bibliographic Details
Main Author: Merlo, Marco
Format: eBook
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Genetics
Mitochondrial Dysfunction
Arrhythmias
Gene Therapy
Non-sense Mrna Decay
Titin
Rna Binding Motif Protein 20 (rbm20)
N/a
Nt-probnp
Dilated Cardiomyopathy
Phosphorylation
Left Ventricular Reverse Remodelling
Desmin
Membrane Stabilization
Left Ventricle Non-compaction Cardiomyopathy
Medicine / Bicssc
Myopathy
Congestive Heart Failure
Cardiac Magnetic Resonance Imaging
Epigenetics
Sex Differences
Systolic Dysfunction
Cardiomyopathy
Congenital Heart Disease
Malignant Ventricular Arrhythmia
Heart Failure
Diastolic Dysfunction
Long-term Outcomes
Phospholamban
Scn5a
Heart
Arrhythmic Risk Stratification
Cardiac Resynchronization Therapy
Cardiac Channelopathy
Laminopathy
Whole Exome Sequencing
Dna Methylation
Biomarkers
Mdx
Long Axis Strain
Serca2a
Ventricular Arrhythmia
Calcium
Left Ventricular Noncompaction
Cardiac Sodium Channel
Muscular Dystrophy
Non-ischemic Cardiomyopathy
Cardiac Magnetic Resonance
Duchenne Muscular Distrophy
Left Atrial Strain
Oxidative Stress
Major Adverse Cardiovascular Events
Nonischemic Dilated Cardiomyopathy
Supraventricular Arrhythmia
Sarcomere
Left Ventricle Sphericity Index
Lmna
Mammalian Target Of Rapamycin (mtor) Complex-1
Precision Medicine
Troponin T
Late Gadolinium Enhancement
Tachycardiomyopathy
Atrial Fibrillation
Alternative Splicing
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis and uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the western world. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, several emerging issues remain debated. Specifically, the genotype-phenotype correlation, the role of advanced imaging techniques and genetic testing, the lack of appropriate risk stratification models, the need for a multiparametric and multidisciplinary approach for device implantation, and a continuous reclassification of the disease during follow-up remain challenging issues in clinical practice. Therefore, the aim of this Special Issue is to shed the light on the most recent advancements in characterization and clinical management of DCM in order to unveil the conundrum of this particular disease.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (232 p.)
ISBN:9783039437627
9783039437610
books978-3-03943-762-7

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