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Stem Cell Bioprocessing and Manufacturing

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. Howev...

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Bibliographic Details
Main Author: Cabral, Joaquim M. S.
Other Authors: Lobato da Silva, Cláudia, Diogo, Maria Margarida
Format: eBook
Language:English
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Computational Fluid Dynamics
Human Pluripotent Stem Cells
Axonal Regeneration
Scalable Manufacturing
Allogeneic Cell Therapy
Human Adipose Stem Cells (hascs)
Olfactory Ensheathing Cells
Infrapatellar Fat Pad
Advanced Therapy Medicinal Products
Turbulent Energy Dissipation Rates
Non-parenchymal Liver Cells
Adipose Stem Cells
Adipose-derived Stem Cell
Fibrin Nerve Conduits
Ursuppe Stem Cell Culture Medium
Neural Regeneration
Scale Up
Spinal Cord Injury
Cell Growth
Segregated And Unstructured Growth Model
Cell Aggregate
N/a
Growth Factors
Knee
Neurotrophic Factors
Lactate
Cell Seeding
Shear Stress
Medicine / Bicssc
Mesenchymal Stromal Cells
Progenitor Cells
Viability
Serum- And Xeno-free Conditions
Single-use Bioreactor
Vertical-wheel
Peripheral Nerve Injuries
Bioreactor
Live-cell Electrospinning
Cell Culture Techniques
Schwann Cells
Microcarrier
Stromal Vascular Fraction
Tissue Engineering
Model Predictive Control
Drug Screening
High Voltage
Cell Therapies
Disease Modeling
U-shaped Vessel
Hydrogels
Induced Pluripotent Stem Cell
Electrospinning
Human Embryonic Stem Cell
Hepatic Cell Lineages
Embryonic Stem Cells
Arthrotomy
Bio-process
Bioprocess
Expansion
Homogeneous Hydrodynamic Environment
Liver Organoids
Autologous Therapy
Hmscs
Hepatocyte Differentiation
Arthroscopy
Kinetic Growth Modeling
Blood Platelets
Differentiation
Stem Cells Delivery
Stem Cell
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful transfer of laboratory-based practice of stem cell and tissue culture to the clinic as therapeutics through the application of engineering principles and practices. This Special Issue of Bioengineering on Stem Cell Bioprocessing and Manufacturing addresses the central role in defining the engineering sciences of cell-based therapies, by bringing together contributions from worldwide experts on stem cell biology and engineering, bioreactor design and bioprocess development, scale-up, and manufacturing of stem cell-based therapies.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (170 p.)
ISBN:9783039430383
books978-3-03943-039-0
9783039430390

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