Ion Channel Trafficking and Cardiac Arrhythmias
A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane,...
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Other Authors: | , , |
Format: | eBook |
Language: | English |
Published: |
Frontiers Media SA
2018
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Series: | Frontiers Research Topics
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Subjects: | |
Online Access: | |
Collection: | Directory of Open Access Books - Collection details see MPG.ReNa |
Summary: | A well-adjusted expression of cardiac ion channels at the sarcolemma is of crucial importance for normal action potential formation and thus cardiac function. The cellular processes that transport channel proteins from the endoplasmic reticulum towards specified regions on the sarcolemmal membrane, and subsequently take them from the plasma membrane to the protein degradation machinery are commonly known as trafficking. The research field recognizes that aberrant channel trafficking stands at the basis of many congenital and acquired arrhythmias. The collection of papers in this eBook provides state-of-the-art insight into the world of ion channel trafficking research. |
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Item Description: | Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/ |
Physical Description: | 1 electronic resource (123 p.) |
ISBN: | 9782889456437 978-2-88945-643-7 |