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DNA Replication Controls

The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...

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Bibliographic Details
Main Author: Eishi Noguchi ((Ed.))
Format: eBook
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2017
Subjects:
Translesion Synthesis
Replisome
Dna Polymerase
Dna Replication
Dna Helicase
Telomere Replication
Biology, Life Sciences / Bicssc
Cancer
Genomic Instability
Replication Checkpoint
Dna Repair
Replication Stress
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by-nc-nd/4.0/
Physical Description:1 electronic resource (X, 304 p.)
ISBN:9783038425694
9783038425687
books978-3-03842-569-4

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