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210512 ||| eng |
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|a books978-3-03928-393-4
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|a 9783039283934
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|a 9783039283927
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|a Chatgilialoglu, Chryssostomos
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| 245 |
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|a Biomimetic Radical Chemistry and Applications
|h Elektronische Ressource
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| 260 |
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|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2020
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| 300 |
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|a 1 electronic resource (300 p.)
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|a radiosensitizers
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|a DNA replication stress
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|a fragmentation
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|a lipid bilayer membranes
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|a electron transfer
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|a cellular response
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|a reaction mechanism
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|a protein stability
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|a thiyl radicals
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|a miRNAs
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|a peroxidation
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|a oligonucleotides
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|a [1
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|a iron porphyrin
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|a liposomal somatostatin
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|a cell micropolarity maps
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|a copper
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|a therapeutic proteins
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|a circular dichroism
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|a iron-mediated ATRP
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|a 5]-radical translocation
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|a isomerization
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|a modified nucleosides
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|a TD-DFT methods
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|a singlet oxygen
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|a sulfones
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|a oxidative damage
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|a quantum dynamics
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|a thiobases
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|a Biology, life sciences / bicssc
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|a oxidation
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|a EPR spectroscopy
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|a radicals
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|a anomeric spironucleosides
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|a carboazidation
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|a ?-radiolysis
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|a diabetes
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|a 2-thiouracil
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|a nucleosides
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|a cross-link
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|a DNA oxidation
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|a genomic and epigenomic instability
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|a stationary radiolysis
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|a pulse radiolysis
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|a retarded delivery
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|a inhomogeneous reactions
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|a ?OH and ?N3 radicals
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|a DNA damage
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|a azides
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|a bio-mimicking catalyst
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|a type 2 diabetes
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|a histone modifications
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|a azidoalkylation
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|a time-resolved spectroscopy
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|a electron holes
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|a oxidative DNA damage
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|a catalase activity
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|a ATRPase
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|a oxononenal
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|a photolysis
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|a reactive aldehydes
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|a gold nanoparticles
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|a DNA hole transfer
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|a DNA
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|a protein labeling
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|a radical reaction
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|a guanine quadruplexes
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|a chemical nuclease
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|a Fenton reaction
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|a laser flash photolysis
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|a heme
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|a iron(IV)-oxo
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|a hydrogen peroxide
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|a trans lipid
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|a 8-oxo-dG
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|a nucleobase derivatives
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|a charge transfer
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|a albumin
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|a beta cells
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|a gamma radiolysis
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|a photo-ionization
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|a DNA methylation
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|a kinetic studies
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|a lipidomics
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|a replication fork stalling
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|a 1
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|a Julia-Kocienski olefination
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|a membrane fluidity maps
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|a 5?
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|a mitochondrial uncoupling protein
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|a 2c-3e S?S-bonded intermediates
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|a free radicals
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|a glycogen phosphorylase
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|a free fatty acids
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|a Raman spectroscopy
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|a hydroxynonenal
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|a intercalation
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|a 8-cyclopurines
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|a biomimetic radical reaction
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|a bioinspired chemical catalysis
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|a 6-dioxa-4-azaspiro[4.5]decane
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|a free radical oxidation
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|a confocal microscopy
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b DOAB
|a Directory of Open Access Books
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| 500 |
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|a Creative Commons (cc), https://creativecommons.org/licenses/by-nc-nd/4.0/
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| 028 |
5 |
0 |
|a 10.3390/books978-3-03928-393-4
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| 856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/42284
|z DOAB: description of the publication
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| 856 |
4 |
0 |
|u https://www.mdpi.com/books/pdfview/book/2134
|7 0
|x Verlag
|3 Volltext
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0 |
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|a 700
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|a The enormous importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted a strong interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment that is suitably designed to be in strict connection with cellular conditions. This Special Issue gives the reader a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to also be used as traces for the discovery of some relevant biological processes. Several subjects are presented, with 12 articles and 6 reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications, and bioinspired synthesis, having "free radicals" as a common denominator.
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