Mathematical, Computational and Experimental T Cell Immunology

The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modell...

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Bibliographic Details
Other Authors: Molina-París, Carmen (Editor), Lythe, Grant (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2021, 2021
Edition:1st ed. 2021
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Cytokine receptor signaling and CD4/CD8 lineage choice during T cell development in the thymus
  • An agent-based model of T helper cell fate decisions in the thymus
  • Modelling naive T cell homeostasis
  • Mechanistic models of CD4 T cell homeostasis and reconstitution in health and disease
  • Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION
  • Modelling the response to Interleukin-7 therapy in HIV-infected patients
  • Modeling immunopathology during persistent viral infections
  • Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation
  • Inferring differentiation order in adaptive immune responses from population level data
  • Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes
  • The public face and private lives of T cell receptor repertoires
  • Population dynamics of immune repertoires
  • Mathematical Modelling of T cell activation
  • Agent-based model of heterogeneous T cell activation in vitro
  • CTLA-4 mediated ligand trans-endocytosis: a stochastic model
  • Automated gating and dimension reduction of high-dimensional cytometry data
  • Index