Computer-aided applications in pharmaceutical technology

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experi...

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Bibliographic Details
Main Author: Djuris, Jelena
Format: eBook
Language:English
Published: Cambridge, UK Woodhead Publishing 2013
Series:Woodhead Publishing series in biomedicine
Subjects:
Online Access:
Collection: O'Reilly - Collection details see MPG.ReNa
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245 0 0 |a Computer-aided applications in pharmaceutical technology  |c edited by Jelena Djuris 
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300 |a 269 pages  |b illustrations (some color 
505 0 |a Includes bibliographical references and index 
505 0 |a 1 Quality-by-design in pharmaceutical development / Jelena Djuris, Svetlana Ibric, and Zorica Djuric, University of Belgrade -- 2 Computer-aided formulation development / Ljiljana Djekic, Dragana Vasiljevic, and Marija Primorac, University of Belgrade -- 3. Experimental design application and interpretation in pharmaceutical technology / Jelena Djuris, Svetlana Ibric, and Zorica Djuric, University of Belgrade -- 4. Chemometric methods application in pharmaceutical products and processes analysis and control / Jelena Djuris, Svetlana Ibric, and Zorica Djuric, University of Belgrade -- 5. Neural computing in pharmaceutical products and process development / Jelena Djuris, Svetlana Ibric, and Zorica Djuric, University of Belgrade -- 6. Computer-aided biopharmaceutical characterization : gastrointestinal absorption simulation / Sandra Grbic, Jelena Parojcic, and Zorica Djuric, University of Belgrade -- 7. Computational fluid dynamics : applications in pharmaceutical technology / Ivana Masic, Jelena Parojcic, and Zorica Djuric, University of Belgrade 
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520 |a Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology. A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technologyCase studies are presented in order to facilitate understanding of various concepts in computer-aided applications