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201006 ||| eng |
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|a 9783030603274
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| 100 |
1 |
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|a Abate, Alessandro
|e [editor]
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| 245 |
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|a Computational Methods in Systems Biology
|h Elektronische Ressource
|b 18th International Conference, CMSB 2020, Konstanz, Germany, September 23–25, 2020, Proceedings
|c edited by Alessandro Abate, Tatjana Petrov, Verena Wolf
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| 250 |
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|a 1st ed. 2020
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| 260 |
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|a Cham
|b Springer International Publishing
|c 2020, 2020
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| 300 |
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|a XIX, 387 p. 208 illus., 57 illus. in color
|b online resource
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|a Classifier Construction in Boolean Networks Using Algebraic Methods -- Sequential Temporary and Permanent Control of Boolean Networks -- Inference and Identification -- ABC(SMC) 2: Simultaneous Inference and Model Checking of Chemical Reaction Networks -- Parameter Synthesis for Hybrid Systems from Hybrid CTL Specifications -- Core Models of Receptor Reactions Evaluate Basic Pathway Designs Enabling Heterogeneous Commitments to Apoptosis -- Drawing the Line: Basin Boundaries in Safe Petri Nets -- Tools -- ModRev - Model Revision Tool for Boolean Logical Models of Biological Regulatory Networks -- fnyzer: a Python Package for the Analysis of Flexible Nets -- eBCSgen: A Software Tool for Biochemical Space Language -- What is a Cell Cycle Checkpoint ? The TotemBioNet Answer -- Kaemika App, Integrating Protocols and Chemical Simulation -- Tutorials -- Tutorial: The CoLoMoTo Interactive Notebook, Accessible and Reproducible Computational Analyses for Qualitative Biological Networks --
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|a Modelling and Analysis -- Rate Equations For Graphs -- Stationary Distributions and Metastable Behaviour for Self-Regulating Proteins with General Lifetime Distributions -- Accelerating Reactions at the DNA Can Slow Down Transient Gene Expression -- Graphical Conditions for Rate Independence in Chemical Reaction Networks -- Interval Constraint Satisfaction and Optimization for Biological Homeostasis and Multistationarity -- Growth Dependent Computation of Chokepoints in Metabolic Networks -- On the Complexity of Quadratization for Polynomial Differential Equations -- Comparing Probabilistic and Logic Programming Approaches to Predict the Effects of Enzymes in a Neurogenerative Disease Model -- Boolean Networks -- Control Strategy Identification via Trap Spaces in Boolean Networks -- Qualitative Analysis of Mammalian Circadian Oscillations: Cycle Dynamics and Robustness -- Synthesis and Simulation of Ensembles of Boolean Networks for Cell Fate Decision --
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| 505 |
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|a Integrating Experimental Pharmacology and Systems Biology for GPCR Drug Discovery
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| 653 |
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|a Computer Communication Networks
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| 653 |
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|a Bioinformatics
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| 653 |
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|a Software engineering
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| 653 |
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|a Computer science
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| 653 |
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|a Mathematics of Computing
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| 653 |
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|a Computer science / Mathematics
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| 653 |
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|a Computational and Systems Biology
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| 653 |
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|a Software Engineering
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| 653 |
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|a Artificial Intelligence
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| 653 |
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|a Computer networks
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| 653 |
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|a Artificial intelligence
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| 653 |
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|a Theory of Computation
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| 700 |
1 |
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|a Petrov, Tatjana
|e [editor]
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| 700 |
1 |
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|a Wolf, Verena
|e [editor]
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| 041 |
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7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
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|a Lecture Notes in Bioinformatics
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| 028 |
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|a 10.1007/978-3-030-60327-4
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-030-60327-4?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 570.113
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|a 570.285
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| 520 |
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|a This book constitutes the refereed proceedings of the 18th International Conference on Computational Methods in Systems Biology, CMSB 2020, held in Konstanz, Germany, in September 2020.* The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology. * The conference was held virtually due to the COVID-19 pandemic
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