Current Advances in the Science of Osteosarcoma Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models

This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tu...

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Bibliographic Details
Other Authors: Kleinerman, Eugenie S. (Editor), Gorlick, Richard (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2020, 2020
Edition:2nd ed. 2020
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies
  • Genomics and the Immune Landscape of Osteosarcoma
  • RECQ DNA Helicases and Osteosarcoma
  • Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma
  • Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma
  • Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response
  • Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma
  • Wnt Signaling in Osteosarcoma
  • Receptor Tyrosine Kinases in Osteosarcoma: 2019 update
  • The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets
  • Autophagy in OS
  • Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs
  • Exosomes: Dynamic Mediators of Extracellular Communication in the TumorMicroenvironment
  • Comparative Immunology and Immunotherapy of Canine Osteosarcoma
  • Index