Lynch Syndrome Molecular Mechanism and Current Clinical Practice

This book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analys...

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Bibliographic Details
Other Authors: Tomita, Naohiro (Editor)
Format: eBook
Language:English
Published: Singapore Springer Nature Singapore 2020, 2020
Edition:1st ed. 2020
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • 1 Molecular mechanism of Lynch syndrome
  • 2 Clinical features of Lynch syndrome
  • 3 Pathology of Lynch syndrome-associated tumors
  • 4 Immunohistochemistry for mismatch repair proteins
  • 5 Genetic analysis for Lynch syndrome
  • 6 Lynch syndrome-associated gynecological malignancies
  • 7 Lynch syndrome-associated urological malignancies
  • 8 Screening for Lynch syndrome
  • 9 Surveillance Colonoscopy for Lynch Syndrome Patients
  • 10 Surgical approach for colorectal cancer in patients with Lynch syndrome
  • 11 Immunotherapy for Lynch syndrome patients
  • 12 Chemoprevention for Lynch syndrome-associated malignancies
  • 13 International collaboration for Lynch syndrome