Tumor Suppressor Genes Volume 1: Pathways and Isolation Strategies

Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by which they control cancer development and progression. In Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, leading physician scientists and academic res...

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Bibliographic Details
Other Authors: El-Deiry, Wafik S. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana Press 2003, 2003
Edition:1st ed. 2003
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Known Tumor Suppessor Genes and Pathways
  • Growth Control by the Retinoblastoma Gene Family
  • The APC Tumor Suppressor Pathway
  • Hereditary Breast and Ovarian Cancer Genes
  • Hereditary Colon Cancer Genes
  • Patched, Hedgehog, and Skin Cancer
  • Tumor Suppressor Genes in Lung Cancer
  • TP53, hChk2, and the Li-Fraumeni Syndrome
  • Genetic Alterations in Esophageal Cancer
  • PTEN and Cancer
  • VHL and Kidney Cancer
  • p16INK4A and Familial Melanoma
  • The INK4a/ARF Locus and Human Cancer
  • Progression Model of Prostate Cancer
  • Neurofibromatosis Type 1
  • Wilms’ Tumor as a Model for Cancer Biology
  • Inadequate “Caretaker” Gene Function and Human Cancer Development
  • The Regulation of Tumor Suppressor Genes by Oncogenes
  • Identification of Tumor Suppressor Genes
  • Determination of Cancer Allelotype
  • Epidemiological Approaches to the Identification of Cancer Predisposition Genes
  • Characterization of Translocations in Human Cancer
  • Positional Approaches to Cancer Genetics
  • Hybrid Capture of Putative Tumor Suppressor Genes
  • Approaches to Proteomic Analysis of Human Tumors
  • Representational Difference Analysis of Gene Expression
  • Antisense Libraries to Isolate Tumor Suppressor Genes
  • Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes
  • Cross-linking Subtractive Hybridization to Identify Tumor Suppressor Genes
  • Suppression Subtractive Hybridization for Identification and Functional Analysis of Tumor Suppressor Genes
  • SAGE as a Strategy to Isolate Cancer-Related Genes
  • Differential Display Techniques to Identify Tumor Suppressor Gene Pathways
  • Detection of Mismatch Repair Gene Expression in Urologic Malignancies