Metastasis Research Protocols
Although ninety percent of fatal cancer cases involve the spread of a primary tumor, the formation of metastases is still a poorly understood, complex process and a significant problem in the treatment of cancer patients. In Metastasis Research Protocols, leading international investigators describe...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana
2001, 2001
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| Edition: | 1st ed. 2001 |
| Series: | Methods in Molecular Medicine
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Detection Methods for Cellular Markers of Metastatic Potential
- Histopathological Assessment of Metastasis
- Basic Immunocytochemistry for Light Microscopy
- Multiple Labeling Techniques for Fluorescence Microscopy
- Lectin Histochemistry to Detect Altered Glycosylation in Cells and Tissues
- Immunocytochemical Detection and Characterization of Individual Micrometastatic Tumor Cells
- Understanding Metastasis Through Integrin Expression
- Surrogate Markers of Angiogenesis and Metastasis
- Measurement of Microvessel Density in Primary Tumors
- Assessment of Cellular Proliferation by Calculation of Mitotic Index and by Immunohistochemistry
- Flow Cytometric Measurement of Cell Proliferation
- SDS -PAGE and Western Blotting Techniques
- Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography
- Genetic Aspects of Metastasis
- In Situ Hybridization to Localize mRNAs
- Fluorescence itIn Situ Hybridization
- Comparative Genomic Hybridization
- RNA Purification and Quantification Methods
- Northern and Southern Blotting and the Polymerase Chain Reaction to Detect Gene Expression
- Methylation Analysis of CpG Islands
- Detection of MetastaticTumor Cells in Blood by Reverse Transcriptase-Polymerase Chain Reaction
- Differential Display
- Mathematical Modeling of Metastasis
- Predictive Mathematical Modeling in Metastasis