Cytotoxic Drug Resistance Mechanisms
In Cytotoxic Drug Resistance Mechanisms, leading clinical and laboratory scientists describe cutting-edge methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. The protocols contain detailed instructions and extensive troubleshooting tips that allow re...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana
1999, 1999
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| Edition: | 1st ed. 1999 |
| Series: | Methods in Molecular Medicine
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Drug Resistance
- Cell Sensitivity Assays
- Cell Sensitivity Assays
- Cell Sensitivity Assays
- Analysis of Apoptosis in Tissue Sections
- Measurement of P-glycoprotein Function
- Measuring MDR-1 by Quantitative RT-PCR
- Microtiter Plate Technique for the Measurement of Glutathione in Fresh and Cryopreserved Lymphoblasts Using the Enzyme Recycling Method
- Measurement of Reduced Glutathione Using High-Pressure Liquid Chromatography
- Topoisomerase I and II Activity Assays
- 5-Fluorouracil Metabolizing Enzymes
- Measuring DNA Adducts by Immunoassay (ELISA)
- Measuring Drug-DNA Adducts in Individual Cells
- Measurement of Drug-Induced DNA Interstrand Crosslinking Using the Single-Cell Gel Electrophoresis (Comet) Assay
- PCR Analysis of Microsatellite Instability
- O 6-Alkylguanine-DNA Alkyltransferase Assay
- Analysis of the p53 Status of Tumors
- Bcl-2 Family Immunohistochemistry
- Genetic Analysis of Drug Resistance by Fluorescence In Situ Hybridization
- Genetic Analysis of Drug Resistance by Reverse In Situ Hybridization