CADTH Canadian drug expert committee recommendation: Telotristat ethyl (Xermelo -- Ipsen Biopharmaceuticals Canada Inc) indication : for the treatment of refractory carcinoid syndrome diarrhea, in combination with somatostatin analogue (SSA) therapy, in patients inadequately controlled by SSA therapy alone

The CADTH Canadian Drug Expert Committee (CDEC) recommends that telotristat ethyl not be reimbursed for the treatment of refractory carcinoid syndrome diarrhea, in combination SSA therapy, in patients inadequately controlled by SSA therapy alone. Telotristat failed to improve symptoms of importance...

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Bibliographic Details
Corporate Authors: CADTH Canadian Drug Expert Committee, Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health July 2019, 2019
Edition:Version: Final
Series:CADTH common drug review
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:The CADTH Canadian Drug Expert Committee (CDEC) recommends that telotristat ethyl not be reimbursed for the treatment of refractory carcinoid syndrome diarrhea, in combination SSA therapy, in patients inadequately controlled by SSA therapy alone. Telotristat failed to improve symptoms of importance to patients that are associated with diarrhea such as urgency and did not improve a variety of health-related quality of life subscales associated with this condition (fatigue, body image, pain, impact on finances, and social/cognitive functioning). Moreover, telotristat did not improve other symptoms associated with carcinoid syndrome, namely abdominal pain and flushing
Item Description:"Final."
Physical Description:1 PDF file (7 pages)