CADTH Canadian drug expert committee recommendation: Telotristat ethyl (Xermelo -- Ipsen Biopharmaceuticals Canada Inc) indication : for the treatment of refractory carcinoid syndrome diarrhea, in combination with somatostatin analogue (SSA) therapy, in patients inadequately controlled by SSA therapy alone
The CADTH Canadian Drug Expert Committee (CDEC) recommends that telotristat ethyl not be reimbursed for the treatment of refractory carcinoid syndrome diarrhea, in combination SSA therapy, in patients inadequately controlled by SSA therapy alone. Telotristat failed to improve symptoms of importance...
Corporate Authors: | , |
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Format: | eBook |
Language: | English |
Published: |
Ottawa (ON)
Canadian Agency for Drugs and Technologies in Health
July 2019, 2019
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Edition: | Version: Final |
Series: | CADTH common drug review
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Subjects: | |
Online Access: | |
Collection: | National Center for Biotechnology Information - Collection details see MPG.ReNa |
Summary: | The CADTH Canadian Drug Expert Committee (CDEC) recommends that telotristat ethyl not be reimbursed for the treatment of refractory carcinoid syndrome diarrhea, in combination SSA therapy, in patients inadequately controlled by SSA therapy alone. Telotristat failed to improve symptoms of importance to patients that are associated with diarrhea such as urgency and did not improve a variety of health-related quality of life subscales associated with this condition (fatigue, body image, pain, impact on finances, and social/cognitive functioning). Moreover, telotristat did not improve other symptoms associated with carcinoid syndrome, namely abdominal pain and flushing |
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Item Description: | "Final." |
Physical Description: | 1 PDF file (7 pages) |