Prostate Cancer Cellular and Genetic Mechanisms of Disease Development and Progression

The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone si...

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Bibliographic Details
Other Authors: Dehm, Scott M. (Editor), Tindall, Donald J. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2019, 2019
Edition:2nd ed. 2019
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Diet and Lifestyle in Prostate Cancer
  • Dietary Carcinogens and DNA Adducts in Prostate Cancer.-Genetic, Environmental, and Nuclear Factors Governing Genomic
  • Cells of Origin for Prostate Cancer
  • Prostate Cancer Genomic Subtypes
  • Prostate Cancer Transcriptomic Subtypes
  • Immunological complexity of the prostate cancer microenvironment influences the response to immunotherapy
  • The Tumor Microenvironments of Lethal Prostate Cancer
  • The Bone Microenvironment in Prostate Cancer Metastasis
  • Prostate Cancer Energetics and Biosynthesis
  • Canonical and Noncanonical Androgen Metabolism and Activity
  • Germline and Somatic Defects in DNA Repair Pathways in Prostate Cancer
  • The Role of RB in Prostate Cancer Progression
  • Interplay among PI3K/AKT, PTEN/FOXO and AR signaling in prostate cancer
  • Androgen Receptor Dependence
  • WNT/BETA-CATENIN SIGNALING AND PROSTATE CANCER THERAPY RESISTANCE
  • Epigenetic Regulation of Chromatin in Prostate Cancer
  • Oncogenic ETS factors in prostate cancer
  • Neural Transcription Factors in Disease Progression
  • Index