Autophagy dysfunction in lysosomal storage disorders

Bibliographic Details
Main Author: Settembre, Carmine
Format: eBook
Language:English
Published: London Henry Stewart Talks 2019, 2019
Series:Autophagy and lysosomal storage diseases
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Overview of the lysosome and autophagy
  • Lysosomal storage disorders (LSDs)
  • Lysosomal vacuolization
  • Accumulation of LC3+ vesicles
  • Studying co-localization of Lamp1 with LC3 and p62
  • LC3-tandem assay to study AV-lysosome fusion
  • mTORC1 inhibitors and AV-lysosome fusion
  • Pharmacological modulation of autophagy