Meningococcal Vaccines Methods and Protocols
The development of a comprehensive vaccine against Neisseria meningitidis, the causative agent of meningococcal disease, has remained elusive because of bacterial diversity and immunologic evasion. In Meningococcal Vaccines: Methods and Protocols, Andrew Pollard and Martin Maiden have assembled an i...
Other Authors: | , |
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Format: | eBook |
Language: | English |
Published: |
Totowa, NJ
Humana
2001, 2001
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Edition: | 1st ed. 2001 |
Series: | Methods in Molecular Medicine
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Subjects: | |
Online Access: | |
Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Meningococcal Vaccines and Vaccine Developments
- Immune Response and Host-Pathogen Interactions
- Purification of Capsular Polysaccharide
- Protein-Polysaccharide Conjugation
- N-Propionylation
- Outer Membrane Protein Purification
- Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease
- Methods for Manipulation of Transferrin-Binding Proteins
- Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins
- Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics
- Construction of porA Mutants
- Construction of LPS Mutants
- Recombinant Proteins in Vaccine Development
- Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries
- Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity
- Early Experiences with Nasal Vaccines against Meningococcal Disease
- Animal Models for Meningococcal Disease
- Determination of Antibody Responses to Meningococcal Antigens by ELISA
- Immunoblot Analysis of Sera from Patients and Vaccinees
- Serogroup B and C Serum Bactericidal Assays
- A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers
- Whole-Blood Model
- Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry
- T-Cell Responses Against Meningococcal Antigens
- CD4 T-Cell Epitope Mapping
- Epitope Mapping
- Meningococcal Vaccine Trials
- The Introduction of Group C Conjugate Meningococcal Vaccine into the UK.