Improving the use of research evidence in guideline development
Managing conflicts of interest5. Group processes6. Determining which outcomes are important7. Deciding what evidence to include8. Synthesis and presentation of evidence9. Grading evidence and recommendations10. Integrating values and consumer involvement11. Incorporating considerations of cost-effec...
Knowledge Centre for the Health Services at The Norwegian Institute of Public Health (NIPH)
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|Managing conflicts of interest5. Group processes6. Determining which outcomes are important7. Deciding what evidence to include8. Synthesis and presentation of evidence9. Grading evidence and recommendations10. Integrating values and consumer involvement11. Incorporating considerations of cost-effectiveness, affordability and resource implications12. Incorporating considerations of equity13. Adaptation, applicability and transferability14. Reporting guidelines15. Disseminating and implementing guidelines16. Evaluation
The processes, in contrast with traditional approaches that rely heavily on the opinions of experts, demand systematic and transparent approaches to access, synthesise and interpret research evidence; and to integrate that evidence with the other information, values and judgements to formulate recommendations. The need for more rigorous processes is underscored by evidence of inconsistencies between the available evidence and expert recommendations, insufficient use of the available evidence, and other insufficiencies in how guidelines and recommendations are developed. Similar criticisms have been raised and calls have been made for better use of research evidence for health care management and policy making. This report: To inform the WHO Advisory Committee on Health Research's advice to WHO the authors of this report have prepared reviews on the following topics:1. Guidelines for guidelines2. Priority setting3. Group composition and consultation process4.
Major new developments have occurred since the World Health Organisation (WHO) was established that have led governments around the world to reconsider the methods that they use to ensure that decisions about health care are well informed by research evidence. This reflection and subsequent changes in how recommendations about health are developed have been driven by recognition of gaps between available research evidence and what is done in practice, variations in practice and outcomes, concerns about the quality of health care, and rising health care costs. Increasingly governments, professional and consumer organisations are demanding more rigorous processes to ensure that health decisions are well informed by the best available research evidence.
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