Efficacy Analysis in Clinical Trials an Update Efficacy Analysis in an Era of Machine Learning

Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables. Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intens...

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Bibliographic Details
Main Authors: Cleophas, Ton J., Zwinderman, Aeilko H. (Author)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2019, 2019
Edition:1st ed. 2019
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables. Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required. This is the first publication of clinical trials that have been systematically analyzed with machine learning. In addition, all of the machine learning analyses were tested against traditional analyses. Step by step statistics for self-assessments are included. The authors conclude, that machine learning is often more informative, and provides better sensitivities of testing than traditional analytic methods do
Physical Description:XI, 304 p. 295 illus., 44 illus. in color online resource
ISBN:9783030199180