NTP research report on absence of formaldehyde-induced neoplasia in Trp53 haploinsufficient mice exposed by inhalation
Formaldehyde inhalation is linked to nasal cancer and leukemia in humans. Formaldehyde-induced DNA-protein crosslinks and enhanced cell proliferation are important in the pathogenesis of nasal cancer and, potentially, leukemia. Mutations in the tumor suppressor gene Trp53 have been associated with f...
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| Format: | eBook |
| Language: | English |
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Research Triangle Park, North Carolina
National Toxicology Program
2017, [2017]
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| Series: | Research report
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| Collection: | National Center for Biotechnology Information - Collection details see MPG.ReNa |
Table of Contents:
- Includes bibliographical references