Ageing: Lessons from C. elegans

This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our...

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Bibliographic Details
Other Authors: Olsen, Anders (Editor), Gill, Matthew S. (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2017, 2017
Edition:1st ed. 2017
Series:Healthy Ageing and Longevity
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Introduction
  • Effects of aging on the basic biology and anatomy of C. elegans
  • Dauer Formation and Ageing
  • Longevity regulation by insulin/IGF-1 signaling
  • Mitochondrial longevity pathways
  • Influences of Germline Cells on Organismal Lifespan and Healthspan
  • Reproductive Aging
  • Nervous System Ageing
  • Stress Response Pathways
  • Oxidative Stress
  • Genome stability and Protein homeostasis and ageing in C. elegans
  • Translational control of longevity
  • Lipid Metabolism, Lipid Signaling and Longevity
  • Autophagy and ageing
  • Dietary restriction in C. elegans
  • Integration of metabolic signals
  • Microbiota, Probiotic Bacteria and Ageing
  • The Future of Worm Ageing.-Index