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190716 ||| eng |
| 020 |
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|a 9789400777422
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| 100 |
1 |
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|a Patel, Vinood B.
|e [editor]
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| 245 |
0 |
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|a Biomarkers in Liver Disease
|h Elektronische Ressource
|c edited by Vinood B. Patel, Victor R. Preedy
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| 260 |
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|a Dordrecht
|b Springer Netherlands
|c 2020, 2020
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| 300 |
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|a 800 p. 50 illus
|b online resource
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| 505 |
0 |
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|a Alanine Aminotransferase -- PTX3 as a biomarker of liver disease
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| 505 |
0 |
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|a Biological Functions and its Neo-epitope as Hepatic Fibrosis Biomarker -- Fibrinogen α-chain as a serum marker of liver disease -- Monocyte chemotactic protein-1 (cytokine, receptors,and gene polymorphisms) in hepatitis -- Biomarkers for Recurrence of Hepatocellular Carcinoma.-Graft-derived cell-free DNA as a biomarker in liver transplantation -- Serum sialic acid as a biomarker in liver disease -- CD133 and EpCAM as Biomarkers in Liver Diseases -- Traditional markers in liver disease -- Biomarkers of extracellular matrix remodeling in liver diseases --
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| 505 |
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|a biological aspects and clinical applications -- microRNA-155 and microRNA-196b in hepatitis C virus infection -- Immunological biomarkers in liver transplantation -- Phosphatidylethanol and alcohol use in liver disease patients -- Interaction of sialyltransferases, sialidases and sialic acids in liver diseases and applications to biomarker discovery -- Biomarkers to monitor graft function following liver transplantation -- YKL-40 as a biomarker of liver diseases -- Peripheral venous, portal venous, hepatic venous, arterial and intrahepatic cytokine levels as biomarkers and functional correlations -- Histological Biomarkers of Non-Alcoholic Fatty Liver Disease -- Vascular cell adhesion molecule-1 (vcam-1) expression in liver disease -- Bilirubin as a biomarker in liver disease -- Hydroxyproline as a biomarker in liver disease -- Genetic biomarkers of paracetamol-induced acute liver failure --
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| 653 |
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|a Oncology
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| 653 |
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|a Cancer research
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| 653 |
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|a Oncology
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| 653 |
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|a Pharmacology
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| 653 |
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|a Pharmacology/Toxicology
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| 653 |
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|a Cancer Research
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| 700 |
1 |
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|a Preedy, Victor R.
|e [editor]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
0 |
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|a Biomarkers in Disease: Methods, Discoveries and Applications
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| 856 |
4 |
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|u https://doi.org/10.1007/978-94-007-7742-2?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 614.5999
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| 520 |
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|a In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists
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