Clinical review report: Edoxaban (Lixiana)

Taken orally, Edoxaban is a highly selective, direct, and reversible inhibitor of factor Xa. It has a Health Canada indication for the treatment of venous thromboembolism (VTE) (deep vein thrombosis (DVT) and pulmonary embolism (PE)) and the prevention of recurrent DVT and PE. The manufacturer has r...

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Bibliographic Details
Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: Ottawa (ON) Canadian Agency for Drugs and Technologies in Health 2017, June 2017
Series:CADTH common drug review
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Taken orally, Edoxaban is a highly selective, direct, and reversible inhibitor of factor Xa. It has a Health Canada indication for the treatment of venous thromboembolism (VTE) (deep vein thrombosis (DVT) and pulmonary embolism (PE)) and the prevention of recurrent DVT and PE. The manufacturer has requested that edoxaban be reimbursed according to the Health Canada indication. The objective of this report was to perform a systematic review of the beneficial and harmful effects of edoxaban for the treatment of VTE (DVT and PE), and for the prevention of recurrent DVT and PE.
Physical Description:1 PDF file (ix, 88 pages) illustrations