MPG.eBooks - Table of Contents: GPCRs and pain

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Bibliographic Details
Main Author:	Stein, Christoph
Format:	eBook
Language:	English
Published:	London Henry Stewart Talks 2019, 2019
Series:	GPCR signalling in human health and disease
Subjects:	Receptors, G-protein-coupled Signal Transduction Cellular Signal Transduction Nociception G Proteins / Receptors Analgesia Receptors, Opioid Analgesics, Opioid Computer Simulation Pain / Drug Therapy Opioids / Therapeutic Use Nociceptive Pain Ligands Pain
Online Access:	https://hstalks.com/bs/3903 https://hstalks.com/bs/p/1049
Collection:	Henry Stewart Talks - Collection details see MPG.ReNa

Table of Contents:

Anatomical & physiological principles underlying nociception & pain
Examples of GPCR mediating excitatory & inhibitory effects on pain sensation
Cross-talk between excitatory & inhibitory intracellular signalling pathways (GPCR in sensory neurons)
Adverse side effects mediated by opioid receptors in the nervous system
Selective activation of peripheral opioid receptors on sensory neurons in injured tissues
Computational simulation of dynamic opioid receptor-ligand interactions (normal vs. injured)
Novel opioid ligand (NFEPP): analgesia in models of inflammatory pain without adverse side effects