A Practical Guide to Pharmacological Biotechnology
Pharmacological biotechnology is applied to and used to study drug development, working mechanisms, diagnosis, and therapies. This manual is the textbook covering the whole range of experiments related to pharmacology. It also contains basic laboratory safety guidelines along with the basic calculat...
| Main Authors: | , , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Singapore
Springer Nature Singapore
2019, 2019
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| Edition: | 1st ed. 2019 |
| Series: | Learning Materials in Biosciences
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Part1.Introduction
- 1.1 Rules of laboratory safety in a pharmacology laboratory
- 1.2 Commom instruments and their uses used in a pharmacology laboratory
- Part2.General aspects of Pharmacology laboratory
- 2.1 Safety and Risk assessment
- 2.2 Use and Handling of laboratory animals
- 2.3 Experimental design
- 2.4 Essential statistics
- 2.5 Cumulative Dose Response Curve
- 2.6 Toxicology
- 2.7 Basic instruments and techniques in Pharmacology Laboratory
- Part3.Isolated tissues and organs
- 3.1 Basic instruments used for isolated tissue experiments
- 3.2 Organ baths
- 3.3 Smooth muscle preparations
- 3.4 Skeletal muscle preparations
- 3.5 Cardiac muscle preparations
- Part4.Isolated tissues for screening of drugs
- 4.1 Evaluation of antidiabetic agents
- 4.2 Evaluation of antidepressants
- 4.3 Evaluation of antihypertensive agents
- 4.4 Evaluation of antiulcer agents
- 4.5 Evaluation of hepatotoxicity
- 4.6 Evaluation of Antioxidant agents
- 8.3 Patenting cells, cell lines and animals
- 8.4 Ethics in laboratory animal studies
- 8.5 Risk assessment and management
- 8.6 Good laboratory practices
- 4.7 Evaluation of local anaesthetics.-Part5.Genotoxicity and Toxicological studies
- 5.1 The Mouse Lymphoma Assay
- 5.2 The Comet Assay
- 5.3 In vitro Genotoxicity assay
- 5.4 In vitro Teratogenicity Testing
- 5.5 Histopathological studies of animal tissues
- 5.6 Drug poisoning
- Part6.Experimental Animal studies
- 6.1 Pyrogen testing
- 6.2 Collecting blood from mice
- 6.3 Studies on different parameters of blood
- 6.4 Experiment on central nervous system
- 6.5 Evaluation on cardiovascular system
- 6.6 Experiments on GI tract
- Part7.Clinical trials
- 7.1 Clinical Pharmacology and its genesis
- 7.2 National and International agencies and their role in Clinical pharmacology
- 7.3 Stages in drug development and clinical trials
- 7.4 Ethics in Clinical research
- 7.5 Safety assessment in Clinical trials
- Part8.IPR and ethics in animal studies
- 8.1 Intellectual property rights and its different categories
- 8.2 Importance of IPR in drug development