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190201 ||| eng |
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|a 9781493989829
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| 100 |
1 |
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|a Lai, Xin
|e [editor]
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| 245 |
0 |
0 |
|a Computational Biology of Non-Coding RNA
|h Elektronische Ressource
|b Methods and Protocols
|c edited by Xin Lai, Shailendra K. Gupta, Julio Vera
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| 250 |
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|a 1st ed. 2019
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| 260 |
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|a New York, NY
|b Humana
|c 2019, 2019
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| 300 |
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|a XII, 451 p. 78 illus., 65 illus. in color
|b online resource
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| 505 |
0 |
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|a ncRNAs in Inflammatory and Infectious Diseases -- p73-Governed miRNA Networks: Translating Bioinformatics Approaches to Therapeutic Solutions for Cancer Metastasis -- Methods for Annotation and Validation of Circular RNAs from RNAseq Data -- Methods to Study Long Non-coding RNA Expression and Dynamics in Zebrafish using RNA Sequencing -- Workflow Development for the Functional Characterization of ncRNAs -- ncRNA Editing: Functional Characterization and Computational Resources -- Computational Prediction of Functional microRNA – mRNA Interactions -- Tools for Understanding miRNA-mRNA Interactions for Reproducible RNA Analysis -- Computational Resources for Prediction and Analysis of Functional miRNA and their Targetome -- Non-coding RNAs Databases: Current Status and Trends -- Controllability Methods for Identifying Associations between Critical Control ncRNAs and Human Diseases -- Network-based Methods and Other Approaches for Predicting lncRNA Functions and Disease Associations -- Integration ofmiRNA and mRNA Expression Data for Understanding Etiology of Gynecologic Cancers -- Quantitative Characteristic of ncRNA Regulation in Gene Regulatory Networks -- Kinetic Modeling of Competition and Depletion of Shared miRNAs by Competing Endogenous RNAs -- Modeling ncRNA-mediated Circuits in Cell Fate Decision -- Modeling Long ncRNA-mediated Regulation in the Mammalian Cell Cycle
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| 653 |
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|a Bioinformatics
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| 653 |
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|a Medical Genetics
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| 653 |
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|a Computational and Systems Biology
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| 653 |
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|a Medical genetics
|
| 700 |
1 |
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|a Gupta, Shailendra K.
|e [editor]
|
| 700 |
1 |
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|a Vera, Julio
|e [editor]
|
| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
| 989 |
|
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|b Springer
|a Springer eBooks 2005-
|
| 490 |
0 |
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|a Methods in Molecular Biology
|
| 028 |
5 |
0 |
|a 10.1007/978-1-4939-8982-9
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| 856 |
4 |
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|u https://doi.org/10.1007/978-1-4939-8982-9?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 570.285
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| 520 |
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|a This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols aims to provide a state-of-the-art collection of computational methods and approaches that will be of value to researchers interested in ncRNA field
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