Genetic Epidemiology Methods and Protocols
This volume details fast-moving research while providing in-depth descriptions of methods and analytical approaches that are helping to understand the genome and how it is related to complex diseases. Chapters guide the reader through common and rare variation, gene-gene and gene-environment interac...
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| Format: | eBook |
| Language: | English |
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New York, NY
Springer New York
2018, 2018
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| Edition: | 1st ed. 2018 |
| Series: | Methods in Molecular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Introduction to Epidemiological Studies
- Key Concepts in Genetic Epidemiology
- Quality Control of Common and Rare Variants
- Genome Wide Association Studies
- Assessing Rare Variation in Complex Traits
- Meta-analysis of Common and Rare Variants
- Gene-gene and Gene-environment Interactions
- Genetic Association in the HLA Region
- Novel Methods for Family-based Genetic Studies
- Methods for Polygenic Traits
- Multivariate Methods for Meta-analysis of Genetic Association Studies
- Methods of Analysis and Meta-Analysis for Identifying Differentially Expressed Genes
- A Primer in Mendelian Randomization Methodology with a Focus on Utilizing Published Summary Association Data
- Copy Number Variation
- From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS Results
- Translating Human Genetics into Novel Drug Targets