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|a 9781473119987
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|a Sepsis (National Guideline Centre (Great Britain))
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|a Sepsis
|h Elektronische Ressource
|b recognition, assessment and early management : final version
|c developed by the National Guideline Centre, hosted by the Royal College of Physicians
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|a London
|b National Institute for Health and Care Excellence
|c 2016, July 2016
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|a 1 PDF file (583 pages)
|b illustrations
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|a Includes bibliographical references
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|a United Kingdom
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|a Sepsis / diagnosis
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|a Evidence-Based Medicine
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|a Risk Assessment
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|a Sepsis / therapy
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|a National Guideline Centre (Great Britain)
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|a National Institute for Health and Care Excellence (Great Britain)
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|a Royal College of Physicians of London
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|a eng
|2 ISO 639-2
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|b NCBI
|a National Center for Biotechnology Information
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|a NICE guideline
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|u https://www.ncbi.nlm.nih.gov/books/NBK374137
|3 Volltext
|n NLM Bookshelf Books
|3 Volltext
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|a 610
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|a The guideline outlines the immediate actions required for those with suspicion of sepsis and who are at highest risk of morbidity and mortality from sepsis. It provides a framework for risk assessment, treatment and follow-up or "safety-netting" of people not requiring immediate resuscitation
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|a The signs and symptoms of sepsis are usually very non-specific and can be missed if clinicians do not think "could this be sepsis?". In the same way that healthcare professionals consider "could this pain be cardiac in origin?" when presented with someone of any age with chest pain, this guideline aims to make "could this be sepsis?" the first consideration for anyone presenting with a possible infection. Detailed guidelines exist for the management of sepsis in adult and paediatric intensive care units, and by intensive care clinicians called to other settings. To reduce avoidable deaths, people with sepsis need to be recognised early and treatment initiated. This guideline aims to ensure healthcare systems in all clinical settings consider sepsis as an immediate life-threatening condition that should be recognised and treated as an emergency.
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|a Sepsis is a clinical syndrome caused by the body's immune and coagulation systems being switched on by an infection. Sepsis with shock is a life-threatening condition that is characterised by low blood pressure despite adequate fluid replacement, and organ dysfunction or failure. Sepsis is an important cause of death in people of all ages. Both a UK Parliamentary and Health Service Ombudsman enquiry (2013) and UK National Confidential Enquiry into Patient Outcome and Death (NCEPOD, 2015) have recently highlighted sepsis as being a leading cause of avoidable death that kills more people than breast, bowel and prostate cancer combined. Clinicians and healthcare professionals of all kinds, at all levels of seniority and in all clinical settings often find sepsis difficult to diagnose with certainty. Although people with sepsis may have a history of infection, fever is not present in all cases.
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