Potential risks and benefits of gain-of-function research summary of a workshop

On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respirato...

Full description

Bibliographic Details
Main Author: Sharples, Frances Ellen
Corporate Authors: National Research Council (U.S.) Board on Life Sciences, National Research Council (U.S.) Committee on Science, Technology, and Law, Institute of Medicine (U.S.) Board on Health Sciences Policy, Gain-of-Function Research (Symposium) ( 2014, Washington, D.C.)
Other Authors: Husbands, Jo L. ([rapporteur]), Mazza, Anne-Marie ([rapporteur]), Thevenon, Audrey ([rapporteur])
Format: eBook
Language:English
Published: Washington, D.C. National Academies Press [2015], 2015
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting
Item Description:Title from PDF title page
Physical Description:1 PDF file (xiv, 125 pages) illustrations
ISBN:0309367832
9780309367837