Antimicrobial stewardship programs in outpatient settings a systematic review

The majority of antimicrobials prescribed to humans originate in outpatient settings. In making prescribing decisions, primary care providers are faced with patient expectations, and with patient and provider lack of awareness of antimicrobial resistance and lack of understanding of the seriousness...

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Bibliographic Details
Main Authors: Drekonja, Dimitri, Filice, Gregory (Author)
Corporate Authors: Quality Enhancement Research Initiative (U.S.), Minneapolis VA Health Care System (U.S.) VA Evidence Synthesis Program
Format: eBook
Language:English
Published: Washington, DC Department of Veterans Affairs, Health Services Research & Development Service 2014, [2014]
Series:Evidence-based synthesis program
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Drekonja, Dimitri 
245 0 0 |a Antimicrobial stewardship programs in outpatient settings  |h Elektronische Ressource  |b a systematic review  |c prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center, Minneapolis, MN, Timothy J. Wilt, Director ; principal investigators, Dimitri Drekonja, Gregory Filice ; co-investigators, Nancy Greer, Andrew Olson, Timothy J. Wilt ; research associates, Roderick MacDonald, Indulis Rutks 
260 |a Washington, DC  |b Department of Veterans Affairs, Health Services Research & Development Service  |c 2014, [2014] 
300 |a 1 PDF file (iv, 150 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
653 |a United States 
653 |a Drug Utilization / standards 
653 |a Inappropriate Prescribing / prevention & control 
653 |a Anti-Bacterial Agents / therapeutic use 
653 |a Outpatients 
653 |a Ambulatory Care Facilities 
700 1 |a Filice, Gregory  |e [author] 
710 2 |a Quality Enhancement Research Initiative (U.S.) 
710 2 |a Minneapolis VA Health Care System (U.S.)  |b VA Evidence Synthesis Program 
041 0 7 |a eng  |2 ISO 639-2 
989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a Evidence-based synthesis program 
500 |a Title from PDF title page. - "February 2014." 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK274571  |3 Volltext  |n NLM Bookshelf Books  |3 Volltext 
082 0 |a 700 
520 |a The majority of antimicrobials prescribed to humans originate in outpatient settings. In making prescribing decisions, primary care providers are faced with patient expectations, and with patient and provider lack of awareness of antimicrobial resistance and lack of understanding of the seriousness of the antimicrobial resistance problem. Antimicrobial stewardship programs (ASPs) are a focused effort by a health care system or a part of the system (ie, an outpatient clinic) to optimize the use of antimicrobial agents. The goals of an ASP are to improve patient outcomes, decrease adverse consequences including from adverse drug reactions and antimicrobial associated infections (eg, Clostridium difficile diarrhea), reduce or prevent antimicrobial resistance, and deliver cost-effective therapy. The emphasis is on appropriate use, selection, dosing, and duration of antimicrobial therapy. The purpose of this review is to synthesize the evidence about the effectiveness of ASPs implemented in outpatient settings. We categorized ASPs based on the primary focus of the intervention as described by the study author. Our categories are: provider and/or patient education, provider feedback, guidelines, delayed prescribing, communications skills training, restriction, decision support, financial incentives, and laboratory testing. The topic was nominated by Matthew Goetz, MD, Chief, Infectious Diseases, VA Greater Los Angeles Healthcare System, on behalf of the VA Antimicrobial Stewardship Task Force, and is intended to provide a summary of the evidence on outpatient ASPs to guide clinical practice and policy within the Veterans Healthcare System