Management of antiplatelet therapy among patients on antiplatelet therapy for cerebrovascular or peripheral vascular diseases undergoing elective non-cardiac surgery

The perioperative management of antiplatelet therapy (APT) for patients with coronary, cerebrovascular, or peripheral vascular stents remains unclear. After percutaneous coronary intervention, American College of Cardiology (ACC) and American Heart Association (AHA) guidelines recommend delaying ele...

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Bibliographic Details
Main Author: Shekelle, Paul G.
Corporate Authors: West Los Angeles VA Medical Center Evidence-Based Synthesis Program Center, United States Department of Veterans Affairs
Format: eBook
Language:English
Published: Washington, DC Department of Veterans Affairs, Health Services Research & Development Service 2017, 2017
Series:Evidence-based synthesis program
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Shekelle, Paul G. 
245 0 0 |a Management of antiplatelet therapy among patients on antiplatelet therapy for cerebrovascular or peripheral vascular diseases undergoing elective non-cardiac surgery  |h Elektronische Ressource  |c principal investigator, Paul Shekelle; co-investigators, Melinda Maggard-Gibbons, Isomi M Miake-Lye, Christopher P Childers, Sean M O'Neill ; contributing investigators, Selene Mak, Roberta Shanman, Jessica M Beroes 
260 |a Washington, DC  |b Department of Veterans Affairs, Health Services Research & Development Service  |c 2017, 2017 
300 |a 1 PDF file (iii, 27 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
653 |a Platelet Aggregation Inhibitors / adverse effects 
653 |a Stents 
653 |a Perioperative Period 
653 |a Cerebrovascular Disorders / drug therapy 
653 |a Peripheral Vascular Diseases / drug therapy 
653 |a Elective Surgical Procedures 
710 2 |a West Los Angeles VA Medical Center  |b Evidence-Based Synthesis Program Center 
710 2 |a United States  |b Department of Veterans Affairs 
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989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a Evidence-based synthesis program 
500 |a At head of title: QUERI. 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK488237  |3 Volltext  |n NLM Bookshelf Books  |3 Volltext 
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520 |a The perioperative management of antiplatelet therapy (APT) for patients with coronary, cerebrovascular, or peripheral vascular stents remains unclear. After percutaneous coronary intervention, American College of Cardiology (ACC) and American Heart Association (AHA) guidelines recommend delaying elective non-cardiac surgery, ideally 6 months following drug-eluting stent placement and 30 days after bare metal stent placement. For patients on dual antiplatelet therapy (DAPT), ACC/AHA guidelines recommend continuing at least aspirin (ASA) throughout the perioperative period and restarting the P2Y12 inhibitor as soon as possible following surgery. However, this latter recommendation is based on expert opinion and was the focus of a recent ESP report. The conclusion of this report was that studies evaluating APT therapy in patients with coronary stents had significant methodologic limitations and that APT therapy likely has a small impact on perioperative bleeding and major adverse cardiac event (MACE) outcomes, compared to other clinical factors such as operative urgency and timing since stent implantation