Schistosomes, liver flukes and helicobacter pylori

japonicum is possibly carcinogenic to humans; infection with S. mansoni could not be classified. The second monograph, on liver flukes, evaluates data on Opisthorchis viverrini, O. felineus and Clonorchis sinensis. These foodborne trematodes establish a chronic infection of the bile ducts and, more...

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Bibliographic Details
Corporate Authors: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, International Agency for Research on Cancer
Format: eBook
Language:English
Published: Lyon, France International Agency for Research on Cancer 1994, 1994
Series:IARC monographs on the evaluation of carcinogenic risks to humans
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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245 0 0 |a Schistosomes, liver flukes and helicobacter pylori  |h Elektronische Ressource  |c IARC Working Group on the Evaluation of Carcinogenic Risks to Humans 
260 |a Lyon, France  |b International Agency for Research on Cancer  |c 1994, 1994 
300 |a 1 PDF file (270 pages)  |b illustrations 
505 0 |a Inlcudes bibliographical references and cumulative cross index to IARC monographs on the evaluation of carcinogenic risks to humans 
653 |a Helicobacter Infections / complications 
653 |a Host-Parasite Interactions 
653 |a Fascioliasis / complications 
653 |a Risk Assessment 
653 |a Neoplasms / etiology 
653 |a Carcinogenesis 
653 |a Schistosomiasis / complications 
710 2 |a IARC Working Group on the Evaluation of Carcinogenic Risks to Humans 
710 2 |a International Agency for Research on Cancer 
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989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a IARC monographs on the evaluation of carcinogenic risks to humans 
500 |a "This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans which met in Lyon, 7-14 June 1994." 
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520 |a japonicum is possibly carcinogenic to humans; infection with S. mansoni could not be classified. The second monograph, on liver flukes, evaluates data on Opisthorchis viverrini, O. felineus and Clonorchis sinensis. These foodborne trematodes establish a chronic infection of the bile ducts and, more rarely, the pancreatic duct and gall-bladder of humans and other mammals. Most carcinogenicity data centre on the possibility that these trematodes are involved in the development of cholangiocarcinoma or liver cancer. The monograph concludes that infection with O. viverrini is carcinogenic to humans and that infection with C. sinensis is probably carcinogenic to humans; infection with O. felineus could not be classified. The final monograph evaluates data on Helicobacter pylori. More than half of the world's population may be infected with this bacterium, which is responsible for most cases of chronic gastritis and duodenal ulcer.  
520 |a This volume Evaluates the carcinogenic risk to humans posed by infection with three schistosoma trematodes, three liver flukes, and the bacterium Helicobacter pylori. These biological agents were selected for evaluation on the basis of evidence suggesting a causal association between infection and the development of human cancers. The first monograph assesses data on Schistosoma haematobium, S. mansoni, and S. japonicum, the three species which account for the vast majority of schistosomal disease in humans. The most extensive sections evaluate the results of studies of cancer in humans and experimental animals, concentrating on the strength of evidence linking infection with S. haematobium to squamous-cell carcinoma of the urinary bladder, and infection with S. mansoni or S. japonicum to an increased risk for cancers of the gastrointestinal tract. The monograph concludes that infection with S. haematobium is carcinogenic to humans and that infection with S.  
520 |a Citing several studies linking infection to gastric cancer in humans, the monograph concludes that infection with H. pylori is carcinogenic to humans