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|a 9781493975280
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| 100 |
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|a Fondi, Marco
|e [editor]
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| 245 |
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|a Metabolic Network Reconstruction and Modeling
|h Elektronische Ressource
|b Methods and Protocols
|c edited by Marco Fondi
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| 250 |
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|a 1st ed. 2018
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| 260 |
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|a New York, NY
|b Humana
|c 2018, 2018
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| 300 |
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|a XI, 410 p. 103 illus., 92 illus. in color
|b online resource
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| 653 |
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|a Cell Biology
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| 653 |
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|a Cytology
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| 041 |
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7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
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|a Methods in Molecular Biology
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| 028 |
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|a 10.1007/978-1-4939-7528-0
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| 856 |
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|u https://doi.org/10.1007/978-1-4939-7528-0?nosfx=y
|x Verlag
|3 Volltext
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|a 571.6
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| 520 |
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|a This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, MetabolicNetwork Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.
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