Understanding the Gut-Bone Signaling Axis Mechanisms and Therapeutic Implications

This is the first book compiling current research on the gut-bone signaling axis and its implications in the pathophysiology of GI and bone diseases. Rather than focusing on a single mechanism, this book provides the reader with a broad view on gut-bone signaling and the most up-to-date information...

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Bibliographic Details
Other Authors: McCabe, Laura R. (Editor), Parameswaran, Narayanan (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2017, 2017
Edition:1st ed. 2017
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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260 |a Cham  |b Springer International Publishing  |c 2017, 2017 
300 |a XIII, 277 p. 36 illus., 29 illus. in color  |b online resource 
505 0 |a Section I: Gut and Bone Physiology -- 1.Introduction -- 2.GI Research: Physiology and Gut Signaling to other organs -- Section II: Gut-Bone Signaling Pathways -- 3. Intestinal regulation of Calcium-Vitamin D and Regulation of Bone Physiology -- 4. GI Regulation of Incretins and Modulation of Bone -- 5.Intestinal Serotonin Regulation of Bone Physiology -- 5. Gut Microbiome and Bone Physiology -- 6. Intestinal Immune System and Regulation of Bone -- Section III: Gut Pathologies Affecting Bone Health -- 7. Stomach-Bone: Gastric Acid and Calcium Absorption -- 8. Inflammatory  Bowel Disease:  Human IBD and Mouse IBD Models -- 9. Antibiotic Use -- 10. Enteritis and Pathogens: Dysbiosis, Pediatrics and Aging -- 11. Enteritis and Pathogens: Chicken Models -- Section IV: Modulation of the Gut Microbiota to Support Bone Health -- 12. Prebiotics -- 13 -- Probiotics -- 14. Germ Free Applications 
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653 |a Systems biology 
653 |a Human physiology 
653 |a Endocrinology  
653 |a Endocrinology 
700 1 |a Parameswaran, Narayanan  |e [editor] 
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520 |a This is the first book compiling current research on the gut-bone signaling axis and its implications in the pathophysiology of GI and bone diseases. Rather than focusing on a single mechanism, this book provides the reader with a broad view on gut-bone signaling and the most up-to-date information in this rapidly growing area.  The volume is also unique in that it looks at what is known about GI diseases affecting bone and then examines the role of the microbiome and its modulation by pre and probiotics to treat bone disease, placing this topic within the context of gut-bone signaling pathways. Understanding the Gut-Bone Signaling Axis will thus provide an understanding of how various therapies could be applied to this area