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RNA interference functions and mechanisms in animals

Bibliographic Details
Main Author: Carthew, Richard
Format: eBook
Language:English
Published: London Henry Stewart Talks 2017, 2017
Series:RNA interference : principles and applications
Subjects:
Rna, Messenger
Rna, Small Interfering / Physiology
Small Interfering Rna.
Microrna.
Genetic Regulation
Drosophila Melanogaster / Genetics
Ribonuclease Iii.
Micrornas
Gene Expression Regulation
Rna Viruses
Gene Silencing
Argonaute Proteins
Rna Interference
Rna-induced Silencing Complex
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Introduction to selfish genetic elements
  • RNAi as a mechanism to defend against selfish gene replication
  • The Argonaute cycle of RNA binding
  • RNAi represses both viruses and transposable elements
  • Post-transcriptional cleavage of mRNAs
  • Applications of RNAi
  • Dicer and its cofactors process and load RNA into Argonaute
  • Distinct Dicer mechanisms for viral and transposon RNA
  • Virus counter-measures to Dicer
  • mRNAs evolved as gene regulators from RNAi

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