Oligodeoxynucleotides Antisense Inhibitors of Gene Expression
This first-ever book on oligodeoxynucleotides describes in detail the new antisense approach to chemotherapy. It is written by world experts, covers all areas of current knowledge and includes new results. The principle of the antisense approach is that an antisense mRNA base sequence will bind to i...
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| Format: | eBook |
| Language: | English |
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London
Macmillan Education UK
1989, 1989
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| Edition: | 1st ed. 1989 |
| Series: | Topics in Molecular and Structural Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Foreword D.Brown
- Introduction: Strategies and Realities; J.Cohen
- Automated Synthesis of Oligonucleotides and Analogs; M.Caruthers
- Oligodeoxynucleotides Covalently Linked to Intercalating and Reactive Substances: Synthesis, Characterization and Physicochemical Properties; N.T.Thuong, U.Asseline, & T.Monteney-Garestier
- Inhibition of Gene Expression by Oligonucleotides; J.Goodchild
- Nonionic Antisense Oligonucleotides; P.Miller
- Phosphorothioate Oligodeoxynucleotide Analogs; C.Stein & J.Cohen
- Alpha-Oligodeoxynucleotide Analogs; B.Rayner, C.Malvy, J.Paoletti, B.Lebleu, C.Paoletti & J.L.Imbach
- Oligonucleotides Covalently Linked to Intercalating Agents and Nucleic Acid-Cleaving Reagents; C.Helene & J-J.Toulme
- Oligonucleotides Linked to Reactive Groups; D.G.Knorre, V.V.Vlassov & V.F.Zarytova
- Oligonucleotide Recognition of Double Helical DNA by Triple Helix Formation; P.Dervan
- Antisense Oligodeoxynucleotides as a Tool for Studying Cell Regulation: Mechanisms of Uptake and Application to the Study of Oncogene Formation; L.Neckers
- Pharmaceutical Considerations; G.Zon
- Index